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Exploiting homomers to reveal new principles of protein interaction, polymerization and aggregation Investments < €500k European Commission 2016
Pathogenesis of autoimmune neurodegeneration: What causes the immune system to destroy healthy neurons? Investments < €500k European Commission 2016
Visualizing cell maintenance: Chemical tools to investigate the microenvironments of misfolded proteins Investments < €500k European Commission 2016
Proteostasis of aging and stem cells Investments < €500k European Commission 2016
Zinc finger gene therapy in the brain for treating Huntington’s disease Investments < €500k European Commission 2016
Transgenic HD Minipig (TgHD, PIGMOD Center) pigmod.avcr.cz [email protected] Czech Republic Transgenic HD Minipig (TgHD, PIGMOD Center) At present, we are probably the only facility to be breeding TgHD minipigs. We have four generations, around 180 animals. The animals are beiing…
Collection of Gene Edited Cell Lines (Neurobiology Laboratory for Brain Aging & Mental Health, Basal) [email protected] Switzerland Collection of Gene Edited Cell Lines (Neurobiology Laboratory for Brain Aging & Mental Health, Basal) It is a collection setup to support…
Non-Human Primate Model of Parkinson’s disease (University of Fribourg) www.unifr.ch/neuro/rouiller/home [email protected] Switzerland Non-Human Primate Model of Parkinson’s disease (University of Fribourg) Non-human primate (macaque monkey; n=4) model of parkinson disease treated with autologous adult progenitor cells.Behavioral data, imaging (PET) and…
ArcAbeta Mouse (University of Zurich +ETH) www.pi.ethz.ch [email protected] Switzerland ArcAbeta Mouse (University of Zurich +ETH) The arcAbeta mouse belongs to the family of amyloid precursor protein expressing mouse lines. It shows age-dependent amyloid pathology with a strong vascular phenotype. Cognitive…
C. elegans ND Models (CRCHUM – Universite de Montreal) [email protected] Canada C. elegans ND Models (CRCHUM – Universite de Montreal) C. elegans models of neurodegeneration Motor neurone diseases| Alzheimer’s disease and other dementias| Neurodegenerative disease in general Animals| Genetic…
Aging Rodents Platform (Quebec network for research on aging) www.rqrv.com [email protected] Canada Aging Rodents Platform (Quebec network for research on aging) Aging male and female LOU rats a unique model of successful aging; Aging Sprague Dawley male rats submitted or…
Behavioural Tests – Cognition & Motor Function (National Univeristy of Ireland Galway)
Ank3-exon1e Mouse Luciferase Reporter (Royal College of Surgeons in Ireland)
Drosophila models for Huntington’s and Parkinson’s disease (University of Lisbon)
Batseson Centre – Zebrafish (University of Sheffield) www.sheffield.ac.uk/bateson
Induced neuronal progenitor cells derived from patient fibroblasts (University of Sheffield) www.sitran.org [email protected] United Kingdom Induced neuronal progenitor cells derived from patient fibroblasts (University of Sheffield) The iNPC’s are generated to further support the ongoing research in Sheffield but are…
G51D SNCA rat (MRC Centre for Regenerative Medicine) [email protected] United Kingdom G51D SNCA rat (MRC Centre for Regenerative Medicine) CRISPR/Cas9 technology was used by Dr Tomoji Mashimo (Kyoto Univeristy) to introduce a single amino acid mutation (Gly-51-Asp) into the…
Triplication alpha-synuclein iPSCs (MRC Centre for Regenerative Medicine) [email protected] United Kingdom Triplication alpha-synuclein iPSCs (MRC Centre for Regenerative Medicine) Human induced pluripotent stem cells (iPSCs) were established from a family with triplication of the alpha-synuclein gene. A collection of…
TRE-11CGG-GFP (Erasmus MC) [email protected] The Netherlands TRE-11CGG-GFP (Erasmus MC) Doxycycline inducible mouse model expressing a Fmr1 control size of 11CGGs coupled to EGFP under control of a Tet-On promoter to study FXTAS; see Hukema et al. Cell Cycle 2014…
Microglia Cell Model (VU University Medical Center) www.vumc.com [email protected] The Netherlands Microglia Cell Model (VU University Medical Center) Microglia, isolated from post mortem human brain (obtained from the Netherlands Brain Bank) , are used to compare effects of Alzheimer’s, Parkinson’s…
Oxford Parkinson Disease Centre (University of Oxford) www.opdc.ox.ac.uk [email protected] United Kingdom Oxford Parkinson Disease Centre (University of Oxford) BAC trangsenic mouse and rat lines carrying wild-type or mutant variants of SNCA and LRRK2; human iPSC lines carrying mutations in SNCA,…
TgF344-AD (University College Cork) www.ucc.ie [email protected] Ireland TgF344-AD (University College Cork) Rat model of AD (TgF344-AD), which expresses the mutant human transgenes: amyloid precursor protein (APPsw) and presenilin 1 (PS1ΔE9). Alzheimer’s disease & other dementias Animals Yes Apply to PI…
Neuroprogressive and Dementia Disease Research Network Neuroprogressive and Dementia Disease Research Network To promote a culture of clinical research in neurodegenerative disease across Scotland United Kingdom 27/06/2005 Scottish Government Research Networks United Kingdom 2016
NS Park NS Park Ns-Park network is a French national clinical research network on Parkinson’s disease (PD) and movement disorders gathering researchers and clinicians experts in the field. Ns-Park includes the 24 French expert centers for PD designated by the…
Neuratris Neuratris NeurATRIS is a research infrastructure conceived to accelerate the translation of discoveries in basic research into medical innovations for the treatment of diseases of the nervous system. France 01/01/2012 ANR Research Networks France 2016
France Life Imaging (FLI) France Life Imaging (FLI) France Life Imaging bears the ambition to become the privileged point of access to the biomedical imaging research, and gathers under its banner a federative network of research teams and facilities. France…
NHMRC National Institute for Dementia Research (NNIDR) NHMRC National Institute for Dementia Research (NNIDR) To prioritise and boost dementia research in Australia and provide the focus to rapidly translate evidence into policy and practice. Australia 01/07/2015 www.nnidr.gov.au Research Networks Australia…
Swedish Brain Power Swedish Brain Power Swedish Brain Power is a network of world-leading Swedish neuroscientist who work together in the fight against incurable dementia like Alzheimers, Parkinsons and amyotrophic lateral sclerosis (ALS). Swedish Brain Powers research program covers the…
Quebec Network for Research on Aging Quebec Network for Research on Aging Canada 01/04/1995 Fonds de recherche du Québec Santé www.rqrv.com Research Networks Canada 2016
Portuguese Mass Spectrometry Network Portuguese Mass Spectrometry Network Research, education and scientific services Portugal 01/01/2008 FCT Research Networks Portugal 2016
PPBI – Portuguese Platform of BioImaging PPBI – Portuguese Platform of BioImaging The PPBI is a nationwide research infrastructure dedicated to bioimaging and formed by a consortium of Portuguese Research Institutes and Universities. PPBI activity is focused on providing access…
Champalimaud Neuroscience Program Champalimaud Neuroscience Program The Champalimaud Foundation (CF) is a private, not-for-profit, charitable organization dedicated to making advances in biomedical science. The core focus of the CF is to achieve breakthroughs in Neuroscience and Cancer Research. Portugal 10/01/2005…
CONGENTO – Consortium for Genetically Tractable Organisms CONGENTO – Consortium for Genetically Tractable Organisms The advent of model organisms where genetic manipulations became standard procedures revolutionized biomedical research. Among these organisms, fruitflies (Drosophila melanogaster), zebrafish (Danio rerio), and mice (Mus…
Parelsnoer Institute-Parel Neurodegenerative diseases Parelsnoer Institute-Parel Neurodegenerative diseases Collaboration of Dutch UMCs for investigation of Alzheimer’s disease biomarkers Netherlands 01/01/2007 NFU www.parelsnoer.org Research Networks Netherlands 2016
Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED) Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED) CIBERNED’s ultimate goal is to foster scientific and technical research of excellence in the field of human health, with the overall goal…
BrainGainSweden BrainGainSweden Our vision is to to promote a seamless innovation process, from discovery to treatment of the patient, and towards the commercialization of innovations. We are a hub that ties together key players from academia, healthcare, industry, government and patient…
Dementia and Neurodegeneration Network Ireland (DNNI) Dementia and Neurodegeneration Network Ireland (DNNI) DNNI focuses on improving our understanding of the causes and mechanisms of dementia and neurodegeneration, the effectiveness of different models of care, and the policy changes required to…
Irish ALS Research Group [email protected] Ireland Complex genetics of ALS and FTD General (e.g. DNA sequence, proteomic data)|Designed for use in clinical neurosciences research Motor neurone disease No Apply to PI or coordinator at resource GWAS & WGS|Deep Phenotype|Spectral EEG|3T…
CEDER – Center for dementia research Capital Infrastructure Sweden 2016
Swedish Brain Power Capital Infrastructure Sweden 2016
FishMed (FP7-Seventh Framework Programme) Capital Infrastructure European Commission 2016
HARC (FP7-Seventh Framework Programme) Capital Infrastructure European Commission 2016
ITRIBIS – (FP7-Seventh Framework Programme) Capital Infrastructure European Commission 2016
HBP (FP7-Seventh Framework Programme) Capital Infrastructure European Commission 2016
GRIFOLS (Loan under the European Fund for Strategic Investments) Capital Infrastructure European Commission 2016
ADOPT BBMRI-ERIC (Horizon 2020) Capital Infrastructure European Commission 2016
StemBANCC (FP7-IMI-Seventh Framework Programme/Innovative Medicines Initiative) Capital Infrastructure European Commission 2016
HCL- NeuroBioTec – Groupement Hospitalier Est, Lyon Capital Infrastructure France 2016
GIE-Neuro-CEB, Paris – Biobank Capital Infrastructure France 2016
TEFOR, CNRS Capital Infrastructure France 2016
