Category JPND Publications

“Interplay of upper and lower motor neuron degeneration in amyotrophic lateral sclerosis” has been published in the journal Clinical Neurophysiology. This work was supported in part by JPND through the ONWebDUALS project, selected in the 2013 Preventive Strategies call.

“The nasal and gut microbiome in Parkinson’s disease and idiopathic rapid eye movement sleep behavior disorder” has been published in the journal Movement Disorders. This work was supported in part by JPND through the BIOMARKAPD project, selected in the 2011…

“P 28 Voxel-based Morphometry (VBM) subcortical white matter changes correlate with disease progression in amyotrophic lateral sclerosis” has been published in the journal Clinical Neurophysiology. This work was supported in part by JPND through the ONWebDUALS project, selected in the…

“P 30 Voxel-based intensometry of high resolution T1 MRI predicts disease progression in ALS” has been published in the journal Clinical Neurophysiology. This work was supported in part by JPND through the oNWebDUALS project, selected in the 2013 Preventive Strategies…

“FV 10 Automated motor unit counting (MSCAN) in amyotrophic lateral sclerosis” has been published in the journal Clinical Neurophysiology. This work was supported in part by JPND through the ONWebDUALS, selected in the 2013 Preventive Strategies call.

“NEK1 genetic variability in a Belgian cohort of ALS and ALS-FTD patients” has been published in the journal Neurobiology of Aging. This work was supported in part by JPND through the STRENGTH project, selected in the 2012 Risk Factors call.

“Distinct metabolomic signature in cerebrospinal fluid in early parkinson’s disease” has been published in the journal Movement Disorders. This work was supported in part by JPND through the BIOMARKAPD project, selected in the 2011 Biomarkers call.

“DNA strand breaks and TDP-43 mislocation are absent in the murine hSOD1G93A model of amyotrophic lateral sclerosis in vivo and in vitro”  has been published in PLOS ONE. The work was supported OnWebDUALS project, part of the 2013 preventive strategies call, and the SOPHIA project, part…

“Immunobiography and the Heterogeneity of Immune Responses in the Elderly: A Focus on Inflammaging and Trained Immunity” has been published in Frontiers in Immunology. The work was supported in part by the ADAGE project, selected in the 2015 JPco-fuND call.

“Midlife work-related stress is associated with late-life cognition” has been published in the Journal of Neurology. The work was supported in part by JPND through the MIND-AD project, selected in the 2013 Preventive Strategies call.

“Inhibition of γ-Secretase Leads to an Increase in Presenilin-1” has been published in Molecular Neurobiology. This work was supported in part by JPND through the BIOMARKAPD project, selected in the 2011 Biomarkers call.

“Another piece in the progranulin puzzle: special binding between progranulin and prosaposin creates additional lysosomal access” has been published in the Journal of Neurochemistry. This work was supported in part by JPND through the STRENGTH and RiMod-FTD projects, selected in…

“Perspectives of policy and political decision makers on access to formal dementia care: expert interviews in eight European countries” has been published in the journal BMC Health Services Research. This work was supported in part by JPND through the ActifCare…

“Single-cell RNA sequencing: Technical advancements and biological applications” has been published in Molecular Aspects of Medecine. This work was supported in part by JPND through the DAMNDPATHS project, selected in the 2013 cross-disease analysis call.

“Improved method for cannula fixation for long-term intracerebral brain infusion” has been published in the Journal of Neuroscience Methods. This work was supported in part by JPND through the NeuroGEM project, selected in the 2013 cross-disease analysis call, and the…

“Sigma 1 receptor activation modifies intracellular calcium exchange in the G93AhSOD1 ALS model” has been published in the journal Neuroscience. This work was supported in part by JPND through the SOPHIA project, selected in the 2011 Biomarkers call.

“Polygenic Risk Score Analysis of Pathologically Confirmed Alzheimer’s Disease” has been published in the journal Annals of Neurology. This work was supported in part by JPND through the PERADES project, selected in the 2012 Risk Factors call.

“α-Synuclein transfer between neurons and astrocytes indicates that astrocytes play a role in degradation rather than in spreading” has been published in Acta Neuropathologica. This work was supported in part by JPND through the NeuTARGETS project, selected in the 2013…

“KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions” has been published in Cell Reports. This work was supported in part by JPND through the RiMod-FTD project, selected in the 2012 Risk Factors call.

“The role of de novo mutations in the development of amyotrophic lateral sclerosis” has been published in Human Mutation. This work was supported in part by JPND through the STRENGTH project, selected in the 2012 Risk Factors call, and the…

“Detection, risk factors, and functional consequences of cerebral microinfarcts” has been published in The Lancet Neurology. This work was supported in part by JPND through the HARNESS project, selected in the 2016 Brain Imaging Working Groups call.

“Contribution to Alzheimer’s disease risk of rare variants in TREM2, SORL1 and ABCA7 in 1,779 cases and 1,273 controls” will be published in the journal Neurobiology of Aging. This work was supported in part by JPND through the PERADES project,…

“Physico-Pathologic Mechanisms Involved in Neurodegeneration: Misfolded Protein-Plasma Membrane Interactions” has been published in the journal Neuron. This work was supported in part by JPND through the NeuTARGETS project, selected in the 2013 Cross-Disease Analysis call, and through the SYNACTION project,…

“Prospective clinical and DaT-SPECT imaging in premotor LRRK2 G2019S-associated Parkinson disease” has been published in the journal Neurology. This work was supported in part by JPND through the DEMTEST project, selected in the 2011 Biomarkers call.

“Extracellular vesicles: Novel promising delivery systems for therapy of brain diseases” has been published in the Journal of Controlled Release. This work was supported in part by JPND through the ModelPolyQ project, selected in the 2015 JPco-fuND call.

“Does participation in the Meeting Centre Support Programme change the stigma experienced by people with dementia?” has been published in the journal European Psychiatry. This work was supported by JPND through the MEETINGDEM project, selected in the 2012 Healthcare Evaluation…

“Neurofilament markers for ALS correlate with extent of upper and lower motor neuron disease” has been published in the journal Neurology. This work was supported in part by JPND through the STRENGTH  and RiMod-FTD projects, selected in the 2012 Risk…

“Decreased plasma β-amyloid in the Alzheimer’s disease APP A673T variant carriers” has been published in the journal Annals of Neurology. This work was supported in part by JPND through the EADB project, selected in the 2015 JPco-fuND call.

“Epigenetic mechanisms during ageing and neurogenesis as novel therapeutic avenues in human brain disorders” has been published in the journal Clinical Epigenetics. This work was supported in part by JPND through the EPI-AD project, selected in the 2015 JPco-fuND call.

“Influence of arterial hypertension, type 2 diabetes and cardiovascular risk factors on ALS outcome: a population-based study“ has been published in the journal Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. This work was supported in part by JPND through the STRENGTH project,…

“Point mutations in transactive response DNA-binding protein 43 (TDP-43)’s N-terminal domain compromise its stability, dimerization and functions “ has been published in the Journal of Biological Chemistry. This work was supported in part by JPND through the RiMod-FTD project, selected in…

“TRPV4 channels contribute to calcium transients in astrocytes and neurons during peri-infarct depolarizations in a stroke model” has been published in the journal GLIA. This work was supported in part by JPND through the DACAPO-AD project, selected in the 2015…

“Brain white matter demyelinating lesions and amyotrophic lateral sclerosis in a patient with C9orf72 hexanucleotide repeat expansion” has been published in the journal Multiple Sclerosis and Related Disorders. This work was supported in part by JPND through the ONWebDUALS project,…

“Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice” has been published in the journal Acta Neuropathologica Communications. This work was supported in part by JPND through the NeuroGEM project, selected in the 2013 Cross-Disease Analysis call and…

“Imaging and fluid biomarkers in frontotemporal dementia” has been published in the journal Nature Reviews Neurology. This work was supported in part by JPND through the PreFrontALS project, selected in the 2013 Preventive Strategies call.

“Nonmotor Symptoms in Amyotrophic Lateral Sclerosis: A Systematic Review” has been published in the journal International Review of Neurobiology. This work was supported in part by JPND through the ALS-CarE project, selected in the 2012 Healthcare Evaluation call.

“Functional reorganization during cognitive function tasks in patients with amyotrophic lateral sclerosis” has been published in the journal Brain Imaging and Behaviour. This work was supported in part by JPND through the NEEDS in ALS project, selected in the 2012…

  “Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study” has been published in the journal PLOS Medicine. This work was supported in part by JPND through the COURAGE-PD project, selected in…

“The small heat shock protein B8 (HSPB8) efficiently removes aggregating species of dipeptides produced in C9ORF72-related neurodegenerative diseases” has been published in the journal Cell Stress & Chaperones. This work was supported in part by JPND through the CureALS project,…

“Assessment of the factorial validity and reliability of the ALSFRS-R: a revision of its measurement model” has been published in Journal of Neurology. This work has been supported in part by JPND through the SOPHIA project, selected in the 2011 Biomarkers…

“Virtual brain biopsies in amyotrophic lateral sclerosis: Diagnostic classification based on in vivo pathological patterns” has been published in the journal Neurolmage: Clinical. This work was supported in part by JPND through the SOPHIA project, selected in the 2011 Biomarkers…

“Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells” has been published in the journal Nucleic Acids Research. This work was supported in part by JPND through the RiMod-FTD project, selected in the 2012…

“A protocol for manual segmentation of medial temporal lobe subregions in 7 tesla MRI” has been published in the journal NeuroImage: Clinical. This work was supported in part by JPND through the EUFIND project, selected in the 2016 Brain Imaging Working…

“Characterization of pathogenic SORL1 genetic variants for association with Alzheimer’s disease: a clinical interpretation strategy” has been published in the European Journal of Human Genetics. This work was supported in part by JNPD through the PERADES project, selected in the…

“Is survival improved by the use of NIV and PEG in amyotrophic lateral sclerosis? A post-mortem study of 80 ALS patients” has been published in the journal PLOS ONE. This work was supported in part by JPND through the SOPHIA…

“Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins” has been published in the journal Acta Neuropathologica. This work was supported in part by JPND through the NeuTARGETs project, selected in the 2013 Cross-Disease Analysis call,…

“Neuronal DNA Methyltransferases: Epigenetic Mediators between Synaptic Activity and Gene Expression?” has been published in the journal The Neuroscientist. This work was supported in part by JPND through the STAD project, selected in the 2015 JPco-fuND call.

“Omega-3 fatty acids, lipids and apoE lipidation in Alzheimer’s disease: a rationale for multi-nutrient dementia prevention” has been published in the Journal of Lipid Research. This work was supported in part by JPND through the MIND-AD project, selected in the 2013…

“Lumbar puncture in patients with neurologic conditions” has been published in the journal Alzheimer’s & Dementia: Diagnosis Assessment & Disease Monitoring. This work was supported in part by JPND through the BIOMARKAPD project, selected in the 2011 Biomarkers call.

“Consensus guidelines for lumbar puncture in patients with neurological diseases“ was published in the journal Alzheimer’s & Dementia: Diagnosis Assessment & Disease Monitoring. This work was supported in part by JPND through the BIOMARKAPD project, selected in the 2011 Biomarkers…