Category JPND Publications

“Molecular imaging to track Parkinson’s disease and atypical parkinsonisms: New imaging frontiers” has been published in Movement Disorders. This work was supported in part by JPND through the ASAP SynTau project, selected in the 2016 brain imaging call.

“Discovery and functional prioritization of Parkinson’s disease candidate genes from large-scale whole exome sequencing” has been published in Genome Biology. This work was supported in part by JPND through the COURAGE-PD project, selected in the 2012 risk factors call.

“PERK activation mitigates tau pathology in vitro and in vivo“ has been published in EMBO Molecular Medicine. This work was supported in part by JPND through the RiMOD‐FTD project, selected in the 2012 risk factors call.

“Experience matters: neurologists’ perspectives on ALS patients’ well-being” has been published in the Journal of Neurology. This work was supported by JPND through the NEEDS in ALS project, selected for support in the 2012 healthcare evaluation call.

“Developmental Expression of 4-Repeat-Tau Induces Neuronal Aneuploidy in Drosophila Tauopathy Models” has been published in Scientific Reports. This work was supported in part by JPND through the INSTALZ project, selected for support in the 2015 JPco-fuND call.

“Participation restrictions in ambulatory ALS patients: Physical and psychological factors” has been accepted for publication in Muscle & Nerve. This research was supported in part by JPND through the SOPHIA, STRENGTH, and ALSCare projects.

“Healthy ageing in 2016: Obesity in geroscience – is cellular senescence the culprit?” has been published in Nature Reviews Endocrinology. This work was supported in part by JPND through the ADAGE project, selected in the 2015 JPco-fuND call.

“Topological transformations in proteins: effects of heating and proximity of an interface” has been published in Scientific Reports. This work was supported in part by JPND through the MisingLink project, selected in the 2013 Cross-Disease Analysis call.

“Linking Amyotrophic Lateral Sclerosis and Spinal Muscular Atrophy through RNA-transcriptome homeostasis: a genomics perspective” has been accepted for publication in the Journal of Neurochemistry. This work was supported in part by JPND through the Fly-SMALS project, selected for support in…

“Astrocytic calcium release mediates peri-infarct depolarizations in a rodent stroke model” has been published in the Journal of Clinical Investigation. This work was supported in part by JPND through the DACAPO-AD project, selected in the 2015 JPco-fuND call.

“IMP: a pipeline for reproducible reference-independent integrated metagenomic and metatranscriptomic analyses” has been published in Genome Biology. This work was supported in part by JPND through the BIOMARKAPD project, selected in the 2011 biomarkers call.  

“Gene discovery in amyotrophic lateral sclerosis: implications for clinical management” has been published in Nature Reviews Neurology. The authors’ work has been supported by JPND through the STRENGTH, SOPHIA and ALS-CarE projects.

An article titled “17q21.31 duplication causes prominent tau-related dementia with increased MAPT expression” has been published in the journal Molecular Psychiatry. This work was supported in part by JPND through the PERADES project, selected in the 2012 risk factors call.

“Positron emission tomography in amyotrophic lateral sclerosis: Towards targeting of molecular pathological hallmarks” has been published in the European Journal of Nuclear Medicine and Molecular Imaging. This work was supported in part by JPND through the STRENGTH and RiMod-FTD projects.

“Neurofilaments in blood and CSF for diagnosis and prediction of onset in Creutzfeldt-Jakob disease” has been published in Scientific Reports. This work was supported in part by JPND through the BiomarkAPD and Sophia projects, selected in the 2011 biomarkers call,…

“Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer’s and Parkinson’s diseases” has been published in the Journal of Neurology, Neurosurgery & Psychiatry. This work was supported in part by JPND.

“Screening for cognitive dysfunction in ALS: validation of the Edinburgh Cognitive and Behavioural ALS Screen (ECAS) using age and education adjusted normative data” has been published in Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. This research was supported in part by…

“Nanomechanical properties of distinct fibrillar polymorphs of the protein α-synuclein” has been published in Scientific Reports. This work was supported in part by JPND through the NeuTARGETs project, selected in the 2013 call for research projects for cross-disease analysis of…

“Identifying behavioural changes in ALS: Validation of the Beaumont Behavioural Inventory (BBI)” has been published in Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. This work was supported in part by JPND through the ALS-Care project, selected in the 2012 healthcare call.

“Development of an Automated MRI-Based Diagnostic Protocol for Amyotrophic Lateral Sclerosis Using Disease-Specific Pathognomonic Features: A Quantitative Disease-State Classification Study” has been published in PLOS ONE. This work was supported in part by JPND through the SOPHIA project, selected for…

“A Comparative Study of SMN Protein and mRNA in Blood and Fibroblasts in Patients with Spinal Muscular Atrophy and Healthy Controls” has been published in PLOS ONE. This work was supported in part by JPND through the STRENGTH project, selected…

“Motion and emotion: anxiety–axial connections in Parkinson’s disease” has been published in the Journal of Neural Transmission. This work was supported in part by JPND through the APGeM project, selected for support in the 2012 risk factors call.

“ATXN2 Trinucleotide Repeat Length Correlates with Risk of ALS” has been accepted for publication in Neurobiology of Aging. This work was supported in part by JPND through the SOPHIA, STRENGTH, and NETCALS projects.

“Caregiver profiles in dementia related to quality of life, depression and perseverance time in the European Actifcare study: the importance of social health” has been published in Aging & Mental Health. This research was supported by JPND in the 2012…

“An Amyloid-Like Pathological Conformation of TDP-43 Is Stabilized by Hypercooperative Hydrogen Bonds” has been published in Frontiers in Molecular Neuroscience. This work was supported in part by JPND through the RiMod-FTD project, selected for support in the 2012 risk factors…

“A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility” has been published in Cell. This research was supported in part by JPND through the BIOMARKAPD project, selected for support in the 2011 biomarkers call.

“Evaluation of α-synuclein as a novel cerebrospinal fluid biomarker in different forms of prion diseases” has been accepted for publication in Alzheimer’s & Dementia. This work was supported in part by JPND through the DEMTEST project, selected in the 2011…

“Physical and cognitive fitness in young adulthood and risk of amyotrophic lateral sclerosis at an early age” has been published in the European Journal of Neurology. This work was supported in part by JPND through the STRENGTH project, selected in…

“sFIDA automation yields sub-femtomolar limit of detection for Aβ aggregates in body fluids” has been published in Clinical Biochemistry. This work was supported in part by JPND through the BIOMARKAPD project, selected for support in the 2011 biomarkers call.

“Naturally Occurring Autoantibodies against Tau Protein Are Reduced in Parkinson’s Disease Dementia” has been published in PLOS ONE. This work was supported in part by JPND through the SOPHIA, BiomarkAPD and PreFrontAls projects.

“Recommendations for CSF AD biomarkers in the diagnostic evaluation of dementia” has been accepted for publication in Alzheimer’s & Dementia. This work was supported by JPND through the BIOMARKAPD and SOPHIA projects, selected for support in the 2011 biomarkers call.

“Recommendations for CSF AD biomarkers in the diagnostic evaluation of MCI” has been accepted for publication in Alzheimer’s & Dementia. This work was supported by JPND through the BIOMARKAPD and SOPHIA projects, selected for support in the 2011 biomarkers call.

“Replication-Independent Histone Variant H3.3 Controls Animal Lifespan through the Regulation of Pro-longevity Transcriptional Programs” has been published in Cell Reports. This work was supported in part by JPND.

“Widespread structural brain involvement in ALS is not limited to the C9orf72 repeat expansion” has been published in the Journal of Neurology, Neurosurgery & Psychiatry. This work was supported in part by JPND through the SOPHIA project, selected for support…

“Perception of Emotional Facial Expressions in Amyotrophic Lateral Sclerosis (ALS) at Behavioural and Brain Metabolic Level” has been published in PLOS ONE. This work was supported in part by JPND through the Needs in ALS project, selected for support in…

“Factors associated with life satisfaction in Parkinson’s disease” has been published in Acta Neurologica Scandinavica. This work was supported in part by JPND through the CLaSP project, selected for support under the 2012 healthcare call.

“Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons” has been published in Molecular Neurodegeneration. This work was funded in part by JPND through the RiMod-FTD project, selected for support in the 2012…

“Cerebrospinal Fluid Biomarkers in the Diagnosis of Creutzfeldt-Jakob Disease in Slovak Patients: over 10-Year Period Review” has been published in Molecular Neurobiology. This work was supported in part by JPND through the DEMTEST project, selected under the 2011 biomarkers call.

“TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins” has been published in Scientific Reports. This research was supported in part by JPND through the RiMod-FTD project, selected in the 2012 risk factors call.

“Normal Development and Function of T Cells in Proline Rich 7 (Prr7) Deficient Mice” has been published in PLOS ONE. This work was supported in part by JPND through the STAD project, selected in the 2015 JPco-fuND call.

“Like prions: the propagation of aggregated tau and α-synuclein in neurodegeneration” has been published in Brain. This work was supported in part by JPND through the REfrAME project, selected for support in the 2015 JPco-fuND call.

“Influence of cigarette smoking on ALS outcome: a population-based study” has been published in the Journal of Neurology, Neurosurgery, and Psychiatry. This work was supported in part by JPND through the SOPHIA project, selected for support in the 2011 biomarkers…

“Familial Alzheimer’s Disease Lymphocytes Respond Differently Than Sporadic Cells to Oxidative Stress: Upregulated p53-p21 Signaling Linked with Presenilin 1 Mutants” has been published in Molecular Neurobiology. This work was supported in part by JPND through the BIOMARKAPD project, selected for…

“Epigenetic dysregulation of brainstem nuclei in the pathogenesis of Alzheimer’s disease: looking in the correct place at the right time?” has been published in Cellular and Molecular Life Sciences. This work was supported in part by JPND through the EPI-AD…

“C9orf72 expansion differentially affects males with spinal onset amyotrophic lateral sclerosis” has been published in The Journal of Neurology, Neurosurgery, and Psychiatry. This work was supported in part by JPND through the SOPHIA project, selected under the 2011 biomarkers call,…

“Physiology of the fasciculation potentials in amyotrophic lateral sclerosis: which motor units fasciculate?” has been published in The Journal of Physiological Sciences. This work was supported in part by JPND through the ONWebDUALS project, selected under the 2013 preventive strategies…

“Gene therapy for the CNS using AAVs: The impact of systemic delivery by AAV9” has been published in the Journal of Controlled Release. This work was supported in part by JPND through the ModelPolyQ project, selected for support in the 2015…

“Amyotrophic lateral sclerosis: moving towards a new classification system” has been published in The Lancet Neurology. This work was supported in part by JPND through the following projects: SOPHIA, selected for support under the 2011 biomarkers call, STRENGTH, selected for…

“TDP‐43 loss of function inhibits endosomal trafficking and alters trophic signaling in neurons” has been published in The EMBO Journal. This research was supported in part by JPND through the PreFrontALS project, selected for support in the 2013 preventive strategies…

“Loss of Tau protein affects the structure, transcription and repair of neuronal pericentromeric heterochromatin” has been published in Scientific Reports. This research was supported in part by JPND through the INSTALZ project, selected under the 2015 JPco-fuND call.