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CoEN 2015: Pathfinder II funded projects
- Towards a unifying theory of Parkinson’s disease: Investigation of the biochemical and genetic role of Rab GTPases
Dario Alessi (UK), Miratul Muqit (UK), Thomas Gasser (Germany) - Protection of neurons in vitro and in vivo from Synuclein toxicity by molecular tweezers
Erwan Bezard (France), Carlos Matute (Spain), Richard Wade-Martins (UK) - Decoding Presymptomatic white matter changes in Huntington Disease (WIN-HD)
Alexandra Durr (France), Sarah Tabrizi (UK) - Synaptic correlates of learning and memory dysfunction analysed by super-resolution STED microscopy in the hippocampus in vivo
Martin Fuhrmann (Germany), Daniel Choquet (France) - GWAS in AD: focus on microRNA
Sébastien Hébert (Canada), Jean-Charles Lambert (France), Luc Buée (France) - BAFF/APRIL in the central nervous system
Bertrand Huard (France), Stefan Lichtenthaler (Germany) - Therapeutic targeting of impaired lysosomal flux in Alzheimer’s disease
Cora O’Neill (Republic of Ireland), Rebecca Sims (UK) - Novel control of MT5-MMP on amyloidogenic and inflammatory pathways: validation in human iPSCs from Alzheimer patients and potential therapeutic perspectives
Santiago Rivera (France), Alexander Dityatev (Germany) - Identifying effectors of mutant C9Orf72 ALS/FTD to combat neurodegeneration
Kevin Talbot (UK), Georg Haase (France) - Using C. elegans to understand seeding and spreading of tau aggregation
Rebecca Taylor (UK), Della David (Germany) - Mito-ND: Mitochondrial Neurodegeneration
Massimo Zeviani (UK), Peter Heutink (Germany)
More information can be obtained at www.coen.org