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The Scottish Health Survey (SHeS) provides a detailed picture of the health of the Scottish population in private households and is designed to make a major contribution to the monitoring of health in Scotland.
The series aims to:
• estimate the occurrence of particular health conditions
• estimate the prevalence of certain risk factors associated with health
• look at differences between regions and between subgroups of the population
• monitor trends in the population’s health over time
• make a major contribution to monitoring progress towards health targets

The Health Survey for England series was designed to monitor trends in the nation’s health, to estimate the proportion of people in England who have specified health conditions, and to estimate the prevalence of risk factors associated with these conditions. The surveys provide regular information that cannot be obtained from other sources on a range of aspects concerning the public’s health. The surveys have been carried out since 1994 by the Joint Health Surveys Unit of NatCen Social Research and the Research Department of Epidemiology and Public Health at UCL. Individuals are asked for written consent to link their HSE records to mortality and cancer registration data (from HSE 1994 onwards) and to Hospital Episodes Statistics (from HSE 2003 participants onwards).

Each survey in the series includes core questions and measurements (such as blood pressure, height and weight, and analysis of blood and saliva samples), as well as modules of questions on topics that vary from year to year. New topics in 2014 year included hearing and mental health. The achieved sample for the 2014 survey was 8,077 adults (aged 16 and over) and 2,003 children (aged 0-15).

On 1st June 1932, as part of the Scottish Mental Survey, 87,498 Scottish schoolchildren born in 1921 sat the same test of mental ability: the Moray House Test. In 1997, the Universities of Aberdeen and Edinburgh began to search for men and women still living in Scotland who took part in these tests.
On 1st June 1998, about 80 individuals gathered in the Aberdeen Music Hall to re-sit the test exactly 66 years later. Participants were followed-up 5 times over a 10 year period.

Aberdeen University has followed all of the children born in Aberdeen in 1921, 1936 (see Aberdeen Birth Cohort 1936) and 1950-1956 (see Aberdeen Children of the 1950’s) as they grow and age.
Collectively these groups are known as the ABERDEEN BIRTH COHORTS, and have helped to advance our understanding of aging well.

Over the years, researchers have linked the results from these tests to health and social information.
The linked data has been used to answer questions like:
• Does being born very small affect mental health later in life?
• Is the risk of dementia related to childhood intelligence?
• What influences quality of life in old-age?
Participants born in 1921 and 1936 have been invited back for a wide variety of studies at the University. Similar research is being started for the Children of the 1950’s group.

On 4th June 1947, as part of the Scottish Mental Survey, every Scottish schoolchild born in 1936 sat the same test of mental ability: the Moray House Test. In 1997, Professor Lawrence Whalley discovered the Scottish Mental Survey test records at the Scottish Council for Research in Education in Edinburgh and began to trace people who had sat the test in Aberdeen.

Aberdeen University has followed all of the children born in Aberdeen in 1921, 1936 (see Aberdeen Birth Cohort 1936) and 1950-1956 (see Aberdeen Children of the 1950’s) as they grow and age.
Collectively these groups are known as the ABERDEEN BIRTH COHORTS, and have helped to advance our understanding of aging well.

Over the years, researchers have linked the results from these tests to health and social information.
The linked data has been used to answer questions like:
• Does being born very small affect mental health later in life?
• Is the risk of dementia related to childhood intelligence?
• What influences quality of life in old-age?
Participants born in 1921 and 1936 have been invited back for a wide variety of studies at the University. Similar research is being started for the Children of the 1950’s group.

The aim of the Cambridge Centre for Ageing and Neuroscience (Cam-CAN) project is to identify the neural mechanisms underpinning successful cognitive ageing. The study recruitment participants over 18 from resident within Cambridge City and used epidemiological, behavioural, and neuroimaging data to understand how individuals can best retain cognitive abilities into old age. A major aim of the research programme is to understand the nature of brain-cognition relationships across the lifespan, and to highlight the importance of abilities that are maintained into old age.

This population study was not designed to have repeated measures for each participant, but rather as one extended and comprehensive study visit that took place over 3 stages.

This is a feasibility study which has a Longitudinal Cohort design, following up participants at selected time points over a 1 year duration. The study will recruit 2 distinct groups: (1) patients with symptoms of cognitive impairment, and (2) study partners who are cognitively normal. The patients recruited to group 1 will have been recently referred to a Memory Assessment Service by their GP with suspected Mild Cognitive Impairment (MCI) & mild dementia. All patients referred to a Memory Assessment Service for this reason will be potentially eligible for inclusion in the study. Close friends or family members involved in looking after the cognitively impaired participants will also be asked to participate as study partners to attempt to measure the impact that looking after a partner, friend or family member with memory problems can have on a carer’s Quality of Life and other variables such as financial burden. Both cognitively impaired participants and their study partners will be given the option of additionally participating in two sub-studies:

– Mobile data collection: Using a web/mobile app to collect self-reported data on a more regular basis from home

– Wearable device: Using a wearable device that looks like a watch to collect information on activity and sleep

i-Share (Internet-based Students HeAlth Research Enterprise) is a new open and prospective cohort on university students’ health. Participants are registered in the first years of study initially with the Universities of Bordeaux and Versailles-Saint-Quentin many many other French universities are now participating. Students are followed up with yearly assessments.

The study sets 2 main types of objectives:

1. Evaluate the frequency and impact of several diseases that may have immediate or short-term consequences on health and well-being (e.g. stress and depression, migraine, sexually transmitted infectious diseases, etc.).
2. Biomedical research objectives on the determinants of diseases. We have set up a cerebral MRI study and biobank on a sample of about 2000 participants including DNA and RNA.

The Northern Ireland Longitudinal Study (NILS) is a large-scale, representative data-linkage study created by linking data from the Northern Ireland Health Card Registration system to the 1981, 1991, 2001 and 2011 Census returns and to administrative data from other sources. These include vital events registered with the General Register Office for Northern Ireland (such as births, deaths and marriages) and the Health Card registration system migration events data. The result is a 30 year plus longitudinal data set which is regularly being updated. In addition to this rich resource there is also the potential to link further Heath and Social care data in our distinct linkage projects (DLPs).

Selection into the study is based on birth date (day and month): 104 dates throughout the year were selected and if an individual’s date of birth coincided with one of these they were included in the sample. The sample is large – c. 28% of the Northern Ireland population (approximately 500,000 individuals and accounting for approximately 50% of households).

The Northern Ireland Mortality Study (NIMS) is a large-scale data linkage study that links the 1991, 2001 and 2011 Census returns for the whole of the enumerated population (approximately 1.6 million individuals) to subsequently registered mortality data from the General Register Office (GRO). While larger than NILS it is more limited in scope, focusing only on the linkage of mortality data. It allows researchers to focus on more detailed analyses of specific cause of death, some of which may not be possible in NILS because of small numbers in sub-populations and the analysis of less common causes of death (e.g. accidental death). The NIMS dataset is recommended to researchers whose primary interest is in mortality in Northern Ireland. These data are maintained under the same conditions as the NILS and is accessible only under the same constraints.

The Lifelines Cohort Study is a large population-based cohort study and biobank that was established as a resource for research on complex interactions between environmental, phenotypic and genomic factors in the development of chronic diseases and healthy ageing. The Lifelines cohort distinguishes a children’s cohort (aged 0-18), an adult cohort (aged 18-65) and the elderly cohort (aged 65+). The protocol for these three sub-cohorts is largely the same, but focuses in part on the characteristics of the specific participant groups.

Between 2006 and 2013, inhabitants of the northern part of The Netherlands and their families were invited to participate, thereby contributing to a three-generation design. Follow-up visits are scheduled every 5 years, and in between participants receive follow-up questionnaires. Linkage is being established with medical registries and environmental data. Lifelines contains information on biochemistry, medical history, psychosocial characteristics, lifestyle and more. Genomic data are available including genome-wide genetic data of 15638 participants. Fasting blood and 24-h urine samples are processed on the day of collection and stored at -80 °C in a fully automated storage facility. The aim of Lifelines is to be a resource for the national and international scientific community. Requests for data and biomaterials can be submitted to the Lifelines Research Office ([email protected]).

The Lifelines Cohort Study is a large population-based cohort study and biobank that was established as a resource for research on complex interactions between environmental, phenotypic and genomic factors in the development of chronic diseases and healthy ageing. The Lifelines cohort distinguishes a children’s cohort (aged 0-18), an adult cohort (aged 18-65) and the elderly cohort (aged 65+). The protocol for these three sub-cohorts is largely the same, but focuses in part on the characteristics of the specific participant groups.

Between 2006 and 2013, inhabitants of the northern part of The Netherlands and their families were invited to participate, thereby contributing to a three-generation design. Follow-up visits are scheduled every 5 years, and in between participants receive follow-up questionnaires. Linkage is being established with medical registries and environmental data. Lifelines contains information on biochemistry, medical history, psychosocial characteristics, lifestyle and more. Genomic data are available including genome-wide genetic data of 15638 participants. Fasting blood and 24-h urine samples are processed on the day of collection and stored at -80 °C in a fully automated storage facility. The aim of Lifelines is to be a resource for the national and international scientific community. Requests for data and biomaterials can be submitted to the Lifelines Research Office ([email protected]).