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Between 1998 and 2002 the Survey team interviewed over 12,583 Southampton women aged 20 to 34 years. Those who became pregnant after interview were invited to take part in the pregnancy phase of the survey. Women received ultrasound scans at 11, 19 and 34 weeks of pregnancy, and their babies were measured soon after birth. There were 3,158 babies born to women in the study between 1998 and 2007. The survey has followed up these children with home visits at six months, one year, two and three years. A sample of over 1,000 children was seen at 4 years of age, more than 2,000 children at ages 6-7 years, and more than 1,000 at 8-9 years. Current follow-up of children at 11-13 years will continue for a number of years.

The aim is to learn more about the dietary,lifestyle, hormonal and omic factors that influence the health of women and their children.

Last Update 21/09/2017

The original aim of the Metropolit cohort was to follow men from early school age to early mid-life, to explore intergenerational mobility and differential life-chances. In 2001 the cohort was revitalised in order to study the development of chronic diseases in a life course perspective.
The Metropolit cohort comprises all 11532 men born in 1953 in the Copenhagen Metropolitan area who were living in Denmark in 1968. These men have been followed repeatedly since their birth. In brief, we have data from birth certificates (1953) which include information on birth dimensions and father’s occupation. In 1965, 7,987 participated in a school-based survey and completed tests of cognition and enquiries regarding leisure-time activities and social aspirations. Data from draft board examinations at around age 19 have been collected for 11,108 of the men. These data include cognitive testing and health information. In 2004, 6,292 of the men responded to a mailed questionnaire with questions on health and lifestyle. In 2009-2010, 2486 of 7799 eligible cohort members participated in the Copenhagen Ageing Midlife Biobank (CAMB) study which comprised questionnaires, cognitive and physical testing as well as blood sampling. Further, around 300 men selected on their young adult and current cognitive performance have been through a neurophysiological examination including EEG, MRI, fMRI and sleep tests. The cohort has also been followed in nation-wide social and health registers for social life, medical and mental hospital diagnosis as well as cause of death from 1969 to 2016.

Last Update 21/09/2017

BiB – Children
Recruitment Period: 2007-11
Sample size at start or planned sample size if still recruiting: 13,857
Estimated current sample size: 13,500
Age at recruitment: 0

BiB – Mothers
Start date: 2006-10
Sample size at start or planned sample size if still recruiting: 12,453
Estimated current sample size: 12,000
Age at recruitment: 15-49

BiB – Fathers
Start date: 2006-10
Sample size at start or planned sample size if still recruiting: 3,414
Estimated current sample size: 3,000
Age at recruitment: 16-60

Born in Bradford is a long term study of a population cohort of 13,500 children, born at Bradford Royal Infirmary between March 2007 and December 2010, whose health is being tracked from pregnancy through childhood and into adult life. The information collected from the BiB families is being used to find the causes of common childhood illnesses and to explore the mental and social development of this new generation.

The Born in Bradford cohort study offers a unique window of opportunity to initiate an innovative and multidisciplinary programme of research. By recruiting pregnant women, their partners and their newborn babies to the cohort, this study offers the potential to:

  • assess the determinants of childhood and adult disease
  • assess the impact of migration
  • explore the influences of pregnancy and childbirth on subsequent health
  • generate and test hypotheses that have the potential to improve health for some of the most disadvantaged within our society.

The Bradford community provides a unique setting for a birth cohort study exploring the determinants of childhood and adult disease because of its diversity of population and high levels of ill-health.

Last Update 21/09/2017

The Children of the 1950s study is a population-based resource for the study of biological and social influences on health across the life-course and between generations.

Comprising individuals born in Aberdeen, Scotland between 1950 and 1956, this cohort is based on the 12,150 people who took part in the Aberdeen Child Development Survey, a cross-sectional study in a population of all children who were attending an Aberdeen primary school in December 1962. The data collected include information on birth weight, childhood height and weight, tests of cognition and behavioural disorder, and a range of multi-level socio-economic indicators.

In the early 2000s the current vital status and whereabouts of 98.5% of the 12,150 subjects (6276 males, 5874 females) with full baseline data were ascertained. The large majority (81%) of study participants still resided in Scotland and the majority (73%) remained in the Grampian region which incorporates Aberdeen.

Linkages to hospital admissions and other health endpoints captured through the routine Scottish Morbidity Records system have been completed. A postal questionnaire to all surviving cohort members was distributed in 2001, with a response proportion of 63%.

The cohort database is now maintained as a resource for researchers, with over 40 publications to data resulting from interrogation of the data.

Last Update 21/09/2017

TRACK-HD was a prospective observational biomarker study in participants with premanifest and early Huntington’s disease (HD). Track-HD assessed longitudinal data collected at baseline, 12 months, 24 and 36 months at sites in Leiden (Netherlands), London (UK), Paris (France), and Vancouver (Canada). Participants were individuals without HD but carrying the mutant HTT gene (ie, premanifest HD), patients with early HD, and healthy control individuals matched by age and sex to the combined HD groups. Data were collected with 3T MRI, clinical, cognitive, quantitative motor, oculomotor, and neuropsychiatric assessments. TrackOn-HD followed on from TRACK-HD aiming to investigate compensatory mechanisms in premanifest gene carriers. Baseline, 12 and 24 month data was collected from the same four sites on premanifest gene carriers and healthy controls including 3T MRI, task and resting state fMRI, DTI, clinical, cognitive, quantitative motor and neuropsychiatric assessments.

Last update – 11/04/2017

The Norwegian ParkWest study is a prospective population-based longitudinal cohort study of patients with incident Parkinson’s Disease in Western and Southern Norway, with a total base population of more than 1 million inhabitants. The initial cohort comprised of 212 newly-diagnosed and drug-naïve individuals with suspected Parkinson’s disease, who were followed with standardized clinical examinations every 6 months. More comprehensive assessments, including neuropsychological and behavioural evaluations, were conducted at baseline and 1-year of follow-up, and at 2-year intervals thereafter. Currently, study participants are in the 10th year of follow-up. About 110 patients are still in the study.

Last update – 10/04/2017

Initially, the study focus was on perinatal, infant, and early childhood morbidity and mortality. We were particularly interested in breastfeeding patterns and nutritional status, as well as social and environmental factors. Deaths of cohort members were identified by regular visits to all hospitals, cemeteries, offices of civil registrations, and local health authorities, since 1982.

By mid-childhood, the study shifted in emphasis to child care, utilization of health services, selected morbidity indicators, and child development. A random sub-sample of 360 four-year-olds was selected for an in-depth study of psychomotor development.

In adolescence, issues related to sexual and reproductive behaviours (including teenage pregnancies), habits such as smoking and alcohol drinking, mental health, and education became the focus of the investigation. A sub-study investigated oral health in a random sample of 900 adolescents, and an ethnographic study of 96 cohort members, stratified by sex and socioeconomic status, has included repeated in-depth visits from the age of 15 to 30 years, aimed at understanding the role of adolescent development in influencing high-risk behaviours.

In more recent phases, with cohort members being young adults, the main emphasis has shifted to risk factors for chronic disease (including smoking, diet, physical exercise, and overweight), reproductive history, and mental health.

Last update – 21/06/2017

The Airwave Health Monitoring Study was established to evaluate possible health risks associated with the use of TETRA, a digital communication system used by the police forces and other emergency services in Great Britain since 2001. It is a long-term observational study following up the health of the police force with respect to TETRA exposure, and ability to monitor both cancer and non-cancer health outcomes. Around 53,000 participants have been recruited between 2004 and 2015.

Last update – 05/05/2017

The Northern Finland Birth Cohort Studies is an epidemiological and longitudinal research program which aims to promote health and well-being of the population. The prospective data collected from the Northern Finland forms a unique resource, allowing to study the emergence of diseases which can be based on genetic, biological, social or behavioural risk factors.

NFBC includes two longitudinal and prospective birth cohorts of women and offspring collected at 20-year intervals from the same provinces of Oulu and Lapland: The NFBC1966 was set with an expected date of birth in 1966, comprising of 12,068 mothers and 12,231 children (prospective data collection from maternity cards since 16th gestational week on average), and the NFBC1986 with an expected date of birth between July, 1st 1985 and June, 30th 1986, comprising 9,362 mothers and 9,479 children (prospective data collection from 10th gestational week).

Last update – 02/05/2017

In 2009, when it was launched, the Tempo cohort consisted of 1,103 people between the ages of 22 and 35 who had participated in a study on children and adolescents’ health between 1991 and 1999: “Les Enfants de Gazel”.

In 2011, Tempo cohort expanded to:

– include young people aged 18-25 years who have specific health situations and life situations
– increase the number of participants to study infrequent health problems.

In 2011 1,214 people were interviewed. In 2015, 783 people participated in the study and 533 participants returned a saliva collection kit. Saliva samples allow us to identify genetic markers that are associated with addictive behaviours (tobacco, alcohol and cannabis/CBD) in relation to characteristics of people’s lives.

In total 526 respondents responded at least three times, and 334 at least four times, giving us the opportunity to examine health trajectories over time.

Participants in the Tempo cohort were asked about their health, the situations they encountered in their daily lives, their work and family experiences.

Last update – 12/05/2017