Since 1993 the EAS has used systematic recruiting methods to assemble a cohort of over 2,200 elderly individuals from the Bronx, 26% of whom are African American. The EAS sample is broadly representative of the elderly population in one of the poorest and most racially and ethnically diverse urban counties in the United States.

The EAS has developed, tested, and applied strategies designed to meet the recruitment and retention challenges that may arise when conducting research studies with older adults. In 2004, the EAS began using the Registered Voter Lists (RVL) for Bronx County for continuous recruitment efforts. Individuals of at least 70 years of age, Bronx residents, non-institutionalized and English speaking are randomly selected from updated RVL and sent a letter followed by a screening telephone call. Persons who complete the telephone screening battery and agree to participate in clinical follow-up are invited to enroll. Continuing enrollment has resulted in over 2200 participants by 2017.

A family-based cohort study that is embedded in the Genetic Research in Isolated Populations (GRIP) program in the South West of the Netherlands. The aim of this program was to identify genetic risk factors in the development of complex disorders. For the ERF study, 22 families that had at least five children baptized in the community church between 1850-1900 were identified with the help of genealogical records. All living descendants of these couples and their spouses were invited to take part in the study. Data collection started in June 2002 and was finished in February 2005 (n=2065).

A population-based prospective study of cerebro-cardiovascular diseases was begun in 1961 in the town of Hisayama, a suburb of the Fukuoka metropolitan area of Kyushu Island in Japan. In addition, comprehensive surveys of cognitive impairment in the elderly of this town have been conducted since 1985. In 1988, a total of 1,228 residents aged ?60 years (91.1% of the total population in this age group) participated in a screening examination for the present study. After exclusion of 33 subjects who had dementia, 90 who had already had breakfast, 5 who were on insulin therapy, and 81 who could not complete the OGTT, a total of 1,019 subjects without dementia underwent the OGTT. From a total of 1,019 subjects, 2 who died before starting follow-up were excluded, and the remaining 1,017 subjects (437 men and 580 women) were enrolled in this study.

The subjects were followed up prospectively for 15 years, from December 1988 to November 2003 (mean 10.9 years; SD 4.1 years).

The primary objective of the Jackson Heart Study is to investigate the causes of cardiovascular disease (CVD) in African Americans to learn how to best prevent this group of diseases in the future.

Specific objectives include:
• Identification of factors, which influence the development, and worsening of CVD in African Americans, with an emphasis on manifestations related to high blood pressure (such as remodeling of the left ventricle of the heart, coronary artery disease, heart failure, stroke, and disorders affecting the blood vessels of the kidney).
• Building research capabilities in minority institutions at the undergraduate and graduate level by developing partnerships between minority and majority institutions and enhancing participation of minority investigators in large-scale epidemiologic studies.
• Attracting minority students to and preparing them for careers in health sciences.

The Jackson Heart Study conducted three cohort examinations, an initial clinic examination from 2000 to 2004 (Exam1), followed by a second exam from 2005 to 2008 (Exam 2) and a final exam in 2009 to 2013 (Exam 3). Starting in 2001, participants have been contacted annually, and ascertainment of hospitalizations for cardiovascular events and deaths is ongoing.

Convenience sample of centenarians, their siblings, offspring, spouses and a control sample consisting of people born around same time as offspring but who do not have parents surviving beyond average life expectancy for their birth cohort. Age range 40-119 years, with ~2500 centenarians in the sample including 600 semi-supercentenarians (ages 105-109) and 200 supercentenarians (ages 110+ years).

We collect the below listed data at enrolment and then collect vital status, hospitalization, changes in meds and diagnoses, cognitive function (TICS) and physical function (IADS, ADL) over the phone, annually. Local subjects are asked to undergo annual detailed cognitive function testing in person with ultimately, brain donation. Blood sample collected at enrolment for DNA, RNA and plasma for biomarkers and storage.

Study is open to collaborations. Please contact Dr. Perls

The Nurses’ Health Study is a longitudinal population study aimed initially to examine the relation between the use of oral contraceptives, cigarette smoking, and risk of major illnesses in women, mainly cancer and cardiovascular diseases. Since then, the study broadened to include the evaluation of health consequences of many lifestyle practices, including diet, physical activity, and specific forms of hormone therapy.

The participants are registered nurses, aged 30 to 55 years and married at the time of recruitment in 1976, and who lived in the 11 most populous states (California, Connecticut, Florida, Maryland, Massachusetts, Michigan, New Jersey, New York, Ohio, Pennsylvania and Texas).

The NLSY 1979 Cohort is a longitudinal project that follows the lives of 12,686 American youth born between 1957 and 1964. The study was intended to be representative of United States residents, both male and female. It observes the life-course experiences of young adults who were finishing their schooling and were making decisions about education and training, entering the labour market, military service, marriage, and having families. Cohort members are now in their 50s and survey content has turned to age-appropriate topics including health and retirement expectations.

Yearly personal interviews were conducted from 1979 – 1986. In 1987, a telephone interview was conducted. Personal interviews resumed in 1988 and continued yearly until 1994. Since 1994, NLSY79 participants have been interviewed in even-numbered years.

Tracking Parkinson’s, or the PRoBaND study, is a UK-based study of Parkinson’s disease funded entirely by Parkinson’s UK.

There is a wide variation of symptoms and features of Parkinson’s driven by both genetic and external factors.  Our study aims to define and explain these variations by analysing the clinical expression of Parkinson’s in relation to genotypic variation. Tracking Parkinson’s is a multi-centre prospective longitudinal study, informed by epidemiological and biomarker data.

Participants were recruited into three categories:

  • Recent onset patients (diagnosed within the last three years) are followed up at 6-month intervals for four years, then every 18-months for a further three years.
  • Early onset (patients diagnosed before the age of 50) were followed up at one year.
  • Relatives (siblings) of the participants are followed up after three years.

Since 2012, we have been running at 70 sites across the UK.  Recruitment closed in November 2017 and our cohort consists of 2,270 people with Parkinson’s and 344 of their siblings.

NHS Greater Glasgow & Clyde is the study Sponsor and the coordinating study centre is based at the Institute of Neuroscience & Psychology at the University of Glasgow in Scotland.

In 1999 the Swedish Ministry for Social Affairs promoted and supported a national project aimed at monitoring and evaluating the care-of-the-elderly system in Sweden. To achieve these aims, four longitudinal individual-based data collection describing the aging process and encompassing the care system as whole, has been initiated. This project was named The Swedish National study on Aging and Care (SNAC).

SNAC-K is conducted by the Stockholm Gerontology Research Center in collaboration with Aging Research Center (ARC), Karolinska Institutet.

SNAC-K includes two studies: SNAC-K population study and SNAC-K care system study.

The Kungsholmen Project is a longitudinal population-based study on ageing and dementia, carried out by the Stockholm Gerontology Research Center in collaboration with Aging Research Center (ARC), Karolinska Institutet.

The project, which started in 1987, has gathered a 12-year long database and offers information on aging from a multidisciplinary perspective. All persons that were born before 1913 and lived in the Kungsholmen district of Stockholm, were invited to participate (a total of 2368 persons on October 1st, 1987, including both community-dwelling and institutionalized persons). Later, the research additionally included all 90+ old subjects living in the St. Göran parish, an adjacent geographical area. The baseline phase and four follow-ups have been completed, with the last phase concluding in the summer of 2000. Time 1 was the only measurement occasion when a two-phase study design was adopted, with an extensive clinical examination performed after a screening phase. At every other occasion, all participants were interviewed by nurses, clinically examined by physicians, and assessed by psychologists.