i-Share (Internet-based Students HeAlth Research Enterprise) is a new open and prospective cohort on university students’ health. Participants are registered in the first years of study initially with the Universities of Bordeaux and Versailles-Saint-Quentin many many other French universities are now participating. Students are followed up with yearly assessments.

The study sets 2 main types of objectives:

1. Evaluate the frequency and impact of several diseases that may have immediate or short-term consequences on health and well-being (e.g. stress and depression, migraine, sexually transmitted infectious diseases, etc.).
2. Biomedical research objectives on the determinants of diseases. We have set up a cerebral MRI study and biobank on a sample of about 2000 participants including DNA and RNA.

The Three-City Study (3C Study) is a population-based longitudinal study of the relation between vascular diseases and dementia in persons aged 65 years and older. A total of 9,294 participants (3,649 men and 5,645 women) were recruited from three French cities: Bordeaux (2,104), Dijon (4,931) and Montpellier (2,259).

The principal objective is to estimate the risk of dementia (Alzheimer’s disease and other types) that may be attributed to vascular factors.

In follow up 1 and 2 (2001-2004) participants were interviewed and subjected to physical and cognitive testing. In follow up 3 (2005-2012) participants completed a postal questionnaire. The third, fourth, and fith waves of follow-up examinations started in 2006 and finished in 2012. A sixth follow-up is ongoing.

Last update – 03/02/2017