Between 1998 and 2002 the Survey team interviewed over 12,583 Southampton women aged 20 to 34 years. Those who became pregnant after interview were invited to take part in the pregnancy phase of the survey. Women received ultrasound scans at 11, 19 and 34 weeks of pregnancy, and their babies were measured soon after birth. There were 3,158 babies born to women in the study between 1998 and 2007. The survey has followed up these children with home visits at six months, one year, two and three years. A sample of over 1,000 children was seen at 4 years of age, more than 2,000 children at ages 6-7 years, and more than 1,000 at 8-9 years. Current follow-up of children at 11-13 years will continue for a number of years.

The aim is to learn more about the dietary,lifestyle, hormonal and omic factors that influence the health of women and their children.

Last Update 21/09/2017

The Hertfordshire Cohort Study comprises a nationally unique study of 3000 men and women born during the period 1931-1939 and still resident in the English county of Hertfordshire. Information available on these individuals includes birthweight (recorded by the attending midwife), weight at age one year (recorded by a health visitor), the method of infant feeding, and details of childhood illnesses up to age five years. Follow-up of individuals began in 1990 and medical and social histories have been ascertained, as well as detailed anthropometry, blood pressure, glucose tolerance, fasting serum cholesterol and triglycerides, bone density and physical performance. DNA on all participants has been collected and is stored in the MRC Lifecourse Epidemiology Unit, University of Southampton, UK.

The entire cohort is being followed up through primary care and hospital records for clinical outcomes including incident coronary heart disease, cerebrovascular disease, chronic airflow obstruction and fracture. The cohort members are flagged with NHS Digital for notification of deaths.

HCS is part of CLOSER (Cohort & Longitudinal Studies Enhancement Resources) which aims to maximise the use, value and impact of the UK’s longitudinal studies.

Last update: 31/01/2017